.guide-wrap{max-width:720px;margin:0 auto;padding:40px 20px 60px}.guide-breadcrumb{font-size:13px;color:var(--text-3);text-decoration:none;display:inline-block;margin-bottom:16px;transition:color .12s}.guide-breadcrumb:hover{color:var(--blue)}.guide-header{margin-bottom:40px;padding-bottom:32px;border-bottom:1px solid var(--border)}.guide-eyebrow{font-size:11px;font-weight:700;letter-spacing:.1em;text-transform:uppercase;color:var(--green);margin-bottom:10px}.guide-title{font-size:32px;font-weight:800;line-height:1.15;letter-spacing:-.03em;color:var(--text-1);margin-bottom:14px}.guide-lead{font-size:17px;color:var(--text-2);line-height:1.6;margin-bottom:14px}.guide-meta{display:flex;gap:8px;font-size:12px;color:var(--text-4)}.guide-section{margin-bottom:48px}.guide-section h2{font-size:22px;font-weight:700;letter-spacing:-.02em;color:var(--text-1);margin-bottom:14px;margin-top:0}.guide-section p{font-size:15px;color:var(--text-2);line-height:1.75;margin-bottom:14px}.guide-section p:last-child{margin-bottom:0}.guide-callout{background:var(--green-light);border-left:3px solid var(--green);border-radius:var(--radius-md);padding:14px 18px;font-size:14px;color:#065f46;line-height:1.6;margin:20px 0}.guide-compare{display:grid;grid-template-columns:1fr 1fr;gap:12px;margin:20px 0}.compare-col{border-radius:var(--radius-md);padding:18px;text-align:center}.compare-col--bad{background:var(--red-light);border:1px solid #fca5a5}.compare-col--good{background:var(--green-light);border:1px solid #6ee7b7}.compare-label{font-size:11px;font-weight:700;text-transform:uppercase;letter-spacing:.08em;color:var(--text-3);margin-bottom:6px}.compare-val{font-size:32px;font-weight:800;letter-spacing:-.03em;margin-bottom:6px}.compare-col--bad .compare-val{color:var(--red)}.compare-col--good .compare-val{color:var(--green)}.compare-desc{font-size:13px;color:var(--text-2);line-height:1.5}.guide-list-numbered{counter-reset:guide-counter;list-style:none;padding:0;margin:16px 0 0;display:flex;flex-direction:column;gap:16px}.guide-list-numbered li{counter-increment:guide-counter;font-size:15px;color:var(--text-2);line-height:1.7;padding-left:36px;position:relative}.guide-list-numbered li:before{content:counter(guide-counter);position:absolute;left:0;top:2px;width:22px;height:22px;background:var(--blue);color:#fff;border-radius:50%;font-size:11px;font-weight:700;display:flex;align-items:center;justify-content:center}.guide-metric-card{background:var(--surface);border:1px solid var(--border);border-radius:var(--radius-lg);padding:22px 24px;margin-bottom:16px;box-shadow:var(--shadow)}.metric-header{display:flex;align-items:flex-start;gap:14px;margin-bottom:12px}.metric-num{width:32px;height:32px;border-radius:50%;background:var(--blue-light);color:var(--blue);font-size:14px;font-weight:800;display:flex;align-items:center;justify-content:center;flex-shrink:0}.metric-title{font-size:16px;font-weight:700;color:var(--text-1);margin-bottom:2px}.metric-sub{font-size:12px;color:var(--text-3)}.guide-metric-card p{font-size:14px;color:var(--text-2);line-height:1.7;margin-bottom:10px}.metric-how{font-size:13px;color:var(--text-3);background:var(--surface-2);border-radius:var(--radius-sm);padding:10px 12px;margin-top:8px;margin-bottom:12px!important}.metric-cta{display:inline-block;font-size:13px;font-weight:700;color:var(--blue);text-decoration:none;border:1.5px solid var(--blue-mid);border-radius:var(--radius-sm);padding:6px 14px;transition:background .12s,color .12s}.metric-cta:hover{background:var(--blue-light)}.guide-biomarker{border-left:3px solid var(--border);padding:0 0 20px 20px;margin-bottom:20px}.guide-biomarker h3{font-size:16px;font-weight:700;color:var(--text-1);margin-bottom:8px}.guide-biomarker p{font-size:14px;color:var(--text-2);line-height:1.7;margin-bottom:8px}.biomarker-target{background:var(--blue-light);border-radius:var(--radius-sm);padding:8px 12px;font-size:13px;color:var(--blue-dark)}.guide-cadence-table-wrap{overflow-x:auto;margin:16px 0;border-radius:var(--radius-lg);border:1px solid var(--border);box-shadow:var(--shadow)}.guide-cadence-table{width:100%;border-collapse:collapse;font-size:13px}.guide-cadence-table th{background:var(--surface-2);padding:12px 16px;text-align:left;font-size:11px;font-weight:700;letter-spacing:.06em;text-transform:uppercase;color:var(--text-3);border-bottom:1px solid var(--border)}.guide-cadence-table td{padding:14px 16px;border-bottom:1px solid var(--border);color:var(--text-2);vertical-align:top;line-height:1.5}.guide-cadence-table tr:last-child td{border-bottom:none}.cadence-freq{display:inline-block;padding:3px 10px;border-radius:12px;font-size:11px;font-weight:700;white-space:nowrap}.cadence-daily{background:var(--blue-light);color:var(--blue)}.cadence-semi{background:var(--amber-light);color:var(--amber)}.cadence-annual{background:var(--orange-light);color:var(--orange)}.cadence-once{background:var(--purple-light);color:var(--purple)}.guide-tools-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:10px;margin:20px 0}.guide-tool-link{display:flex;flex-direction:column;align-items:center;gap:6px;padding:14px 8px;background:var(--surface);border:1px solid var(--border);border-radius:var(--radius-md);text-decoration:none;color:var(--text-2);font-size:12px;font-weight:600;text-align:center;transition:border-color .12s,background .12s}.guide-tool-link:hover{border-color:var(--blue-mid);background:var(--blue-light);color:var(--blue)}.tool-icon{font-size:20px}.guide-radar-cta{background:linear-gradient(135deg,#4f46e5,#7c3aed);border-radius:var(--radius-lg);padding:24px;text-align:center;color:#fff;margin-top:20px}.guide-radar-cta p{color:#ffffffd9;font-size:15px;margin-bottom:14px}.guide-radar-cta .btn-primary{background:#fff;color:#4f46e5}.guide-radar-cta .btn-primary:hover{background:#f5f3ff}.guide-sources{border-top:1px solid var(--border);padding-top:28px;margin-top:48px}.sources-title{font-size:14px;font-weight:700;color:var(--text-3);margin-bottom:14px;text-transform:uppercase;letter-spacing:.06em}.guide-sources .source-list li{font-size:12px;color:var(--text-4);line-height:1.6}@media(max-width:640px){.guide-title{font-size:24px}.guide-compare{grid-template-columns:1fr}.guide-tools-grid{grid-template-columns:repeat(2,1fr)}.guide-cadence-table{font-size:12px}.guide-cadence-table th,.guide-cadence-table td{padding:10px 12px}}